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Leadership & Restructuring

Biopharma Partnering: Dating Well Before Marriage Serves Its Purpose

For most emerging bio-pharma or medtech companies, establishing a development or commercialization partnership is a core component of their strategic plan, and, sealing the deal is cause for much celebration. While hard work and a number of all-nighters may go into signing an agreement, ensuring the partnership achieves its objectives and sails across the finish line is often harder, and often a bumpy ride...
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Korean Biotech on the Global Stage (Webinar Syneos Health / Treehill Partners)

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Biotech Value Creation (Podcast Syneos Health / Treehill Partners)

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New Opportunities for Value Creation: How Biotechs Can Succeed in an Increasingly Competitive Market (Webinar Syneos Health / Treehill Partners)

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Illiquid Gold: Creative Dealmaking in Biotech (Webinar Evaluate / Treehill Partners)

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Foggy-Brain-Double-Exposure

Innovation Potential in Mental Health

Rising awareness and emergence of differentiated solutions for multiple psychiatric and mental health conditions is an ongoing theme of innovation in pharma but also adjacent and “convergence” fields in healthcare. Increasing incidence, certainly exacerbated by lockdowns and other measures implemented to curtail the spread of COVID-19, and the significant lack of innovation in the past represent the key ingredients for a resurgence, which is currently emerging.
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Businessmen-Handshake-Cityview

Biopharma Partnering: A Fine Art

The majority of pharma and biotech venture creations are aimed at one or both of two fundamental objectives, bringing a novel therapeutic to patients and generating returns for their founders and investors. Often, pathways are poorly understood by the bootstrap team, and professional “help” is being sought from incubators, boards, investors and advisors, embedding possibly conflicting perspectives and goals into the core fabric of the company.
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Digital-Health-Doctor

The Evolving Digital Health Landscape

Capital allocation towards innovative health-tech solutions has fuelled an increase in adoption of digital technologies. We outline a few current themes and future trends in the area.
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Globe-Golden-Numbers

2021 in Retrospect and 2022 Outlook

A month into 2022 and all virtual “JPM meetings” completed, we took a moment to reflect on the past
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Pills-On-Basket-Pharma-Brexit

The Brexit Deal – Shot in the Arm or Kick in the Teeth for the Pharma Sector?

The UK Government and EU Commission trumpeted their last minute Brexit trade deal, struck at the end of December, as comprehensive, the biggest yet. Even allowing for the hyperbole of politicians, a closer inspection of the EU-UK Trade and Cooperation Agreement (TCA) renders these statements illusory for the pharma sector. In this article we summarise the extent to which the TCA really assists businesses in the sector to overcome the separation of the UK and the EU into two separate markets:
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Virtual-Reality-Healthcare

Biopharma Partnering: 2021 – Virtual Reality?

The start of a new year in healthcare has over the past decades been characterized by back-to-back meetings spread across hotel rooms in San Francisco where the industry’s annual gathering had taken place, not to say had been celebrated. Nobody knows if or when we will return to holding physical meetings. What the pandemic has shown us all is that a lot of time can be saved when interacting virtually:
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Small-Boat-Pulling-a-Larger-Tanker

Biopharma Partnering: Striking a Deal with Big Pharma

As what used to be healthcare’s busiest meetings week is going to be a week of virtual interaction around the globe, we thought it worthwhile to share a few considerations on partnering between biotech and large pharma from the perspective of the developing biotech...
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Bio Convention 2019 Debrief

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IPO's-and-Partnering-Chart

Biopharma Partnering: IPOs and Partnering

An initial Public Offering has for decades been the endgame for an aspiring biotech company. Thinking back just 10 years, an IPO was conceivable generally only once a company had successfully brought at least one lead therapeutic into late-stage clinical trials and the pipeline was robust. Today this has changed...
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When-To-Partner

Biopharma Partnering: When To Partner

In late spring when apple trees are filled with young fruits, the best way to ensure a healthy harvest in autumn is to thin out the fruits, which in turn strengthens the tree and helps the remaining fruits grow and ripen.In late spring when apple trees are filled with young fruits, the best way to ensure a healthy harvest in autumn is to thin out the fruits, which in turn strengthens the tree and helps the remaining fruits grow and ripen.While the gardener knows that the autumn harvest will be stronger for doing it, the thinning out process is painful every time...
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Covid-19-Treatment-Strategies

Covid-19 Treatment Strategies

There are two predominantly emerging therapeutic strategies for the development of drugs to treat patients with COVID-19. The first is to target the virus (SARS-CoV2) itself. This is how Remdesivir, the most widely discussed treatment for COVID-19 works. The second therapeutic strategy is to mitigate the effect of cytokine...
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Abstract-Background-Cover

All Great Changes are Preceded by Chaos

The world of healthcare has been turned upside down. The COVID-19 pandemic has taken healthcare systems across the globe to breaking point, with hospitalization rates never before seen and hundreds of thousands of fatalities. While the immediate crisis was characterized by lack of personal protective equipment...
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Man-Climbing-on-a-Cliff

A Ladder with a Rung Missing

Drug development is like climbing a well-defined heavily regulated “ladder”. This ladder has and will always rightly hold the safety of patients subjected to experimental therapies as its number one priority. Each of the steps are clearly defined, and whilst some may intertwine generally include..
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JP Morgan Conference Debrief

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Team-of-Doctors

Doctor Founder Ventures – Biotech Entrepreneurship Essentials

By the very nature of the profession, doctors become “good doctors” by developing strong entrepreneurship qualities. Running an own private practice or being part of a large group practice, each provides for taking on sizable risk and executing resource allocation tasks where one must embody strong communication qualities to see positive outcomes...
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Man-Binoculars-Recruiting-Solutions

A Forced Transition

Running a healthy efficient business is a full-time task for senior management during normal times. The unprecedented transition into a world of uncertainty, paired with unclear timing and nature of recovery, present not only new challenges to navigate but also an unprecedented volume of forced “restructuring” in our industry...
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Philadelphia-Corona-Graph

Corona

Whilst Corona virus news are out there loud and clear, a mindset of “I would survive hence will be taking my chance” made us pause and reply, calmly, that yes you likely would but could carry it to those who would not – and that is the problem. We point out the often quoted comparison of 1918 flu epidemic responses between the two cities...
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Biotech Capital Raising Insights

Treehill Partners operates extensive Healthcare Investment Banking services and world class biotechnology Strategy Consulting as well as Leadership Support advisory services to some of today’s most innovative industry leadership teams. Over the years, as we evaluate investment proposals put forward to corporates, venture capitalists...
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Game Theory & Biotech Alpha Culture

n 1973, John Maynard Smith presented an idea explaining game theory and how alpha culture exists in societies. Maynard’s hypothesis asked you to imagine a world with doves and hawks. If there would be only hawks, their fights would be devastating to their population. If there would be only doves, they would be susceptible to any intruders...
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Fresh from Bio Europe

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Neosurgery-Medical-Device

The Capital Raising Biotech CEO Whose Calls are not Returned

Many CEOs in biotechnology are focused on reaching out to as many investors as possible in a style that is known to be rather hectic and haphazard. A recent study showed that nearly 80% of institutional investors will not invest in a concept they do not understand scientifically. Saying it another way, if investors do not understand...
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Heart-Transplant

Surgeon: “Xenotransplantation Will Become Commonplace”

The process of grafting or transplanting organs or tissues between members of different species, or xenotransplantation, will become commonplace over the next three years, according to Sir Terence English who, in 1979, completed the first successful heart transplant in the United Kingdom. 40 years later, Sir Terrance and his team...
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Biotechnology-Data

Real World Data and Pathways to Biotechnology Market Success

Real World Data (RWD) and Real World Evidence (RWE) are gaining traction across the industry. The front runners are already exploring new ways to collect and use data within their market access strategies and, for some, this is proving an effective way to ‘tip the balance’ from a no to a yes with target agencies...
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Water-Splash

Water’s Health Crisis

Access to clean water ranks amongst the most important drivers of health conditions within a country or region. It is also a key driver of economic productivity or, as many put it, it is the source of life. With information becoming more and more a commodity and accessible to ever larger portions of the global population, the realization that...
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Wifi-Symbol

Pharma Targeting Public Wi-Fi

Traditionally, point of care settings have struggled in providing effective messaging to patients, notably hampered by the cost and scale of setting up physical displays and reference material at individual offices.Use of digital technology at health facilities to connect with patients is seeing results. Data service providers are leveraging IP address targeting...
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